Award details

Functional analysis of a plant protein important for the cell-to-cell movement of potyviruses

ReferenceBBS/B/0658X
Principal Investigator / Supervisor Professor Andrew Maule
Co-Investigators /
Co-Supervisors
Institution John Innes Centre
DepartmentDisease and Stress Biology
Funding typeResearch
Value (£) 233,384
StatusCompleted
TypeResearch Grant
Start date 18/10/2004
End date 17/10/2007
Duration36 months

Abstract

We have identified a family of novel proteins that interact with the virus genome-linked protein (VPg) of a range of potyviruses to support virus movement in compatible infections. Called Potyvirus VPg-Interacting Proteins (PVIP), they are probably essential for plant growth but have no proven function except to support virus movement. In this project, we will investigate 1) the function of PVIP in plants, 2) The cellular and intracellular location of PVIP relative to potyvirus replication and virus particles and 3) how PVIP supports potyvirus movement. The work will contribute to filling the substantial void in our understanding of the factors required for successful infection and provide new information on important plant functions.

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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