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Functional analysis of a plant protein important for the cell-to-cell movement of potyviruses
Reference
BBS/B/0658X
Principal Investigator / Supervisor
Professor Andrew Maule
Co-Investigators /
Co-Supervisors
Institution
John Innes Centre
Department
Disease and Stress Biology
Funding type
Research
Value (£)
233,384
Status
Completed
Type
Research Grant
Start date
18/10/2004
End date
17/10/2007
Duration
36 months
Abstract
We have identified a family of novel proteins that interact with the virus genome-linked protein (VPg) of a range of potyviruses to support virus movement in compatible infections. Called Potyvirus VPg-Interacting Proteins (PVIP), they are probably essential for plant growth but have no proven function except to support virus movement. In this project, we will investigate 1) the function of PVIP in plants, 2) The cellular and intracellular location of PVIP relative to potyvirus replication and virus particles and 3) how PVIP supports potyvirus movement. The work will contribute to filling the substantial void in our understanding of the factors required for successful infection and provide new information on important plant functions.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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