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Amino acid shuttling in the legume-Rhizobium symbiosis

Reference	BBS/B/02916
Principal Investigator / Supervisor	Professor Philip Poole
Co-Investigators / Co-Supervisors	Miss Emma Lodwig
Institution	University of Reading
Department	Animal and Microbial Sciences
Funding type	Research
Value (£)	324,736
Status	Completed
Type	Research Grant
Start date	04/05/2004
End date	03/05/2007
Duration	36 months

Abstract

We have recently proposed that nitrogen fixation by Rhizobium-legume symbioses is driven by amino acid cycling. Instead of the plant simply providing dicarboxylic acids to the bacterial microsymbiont in return for ammonium secretion, the whole process is driven by cycling of amino acids in both directions. Determining which amino acids are cycled and how this process is regulated is central to understanding the biochemical basis of nitrogen fixation by legume-Rhizobium symbioses. I propose to determine which amino acids are cycled by using a series of overlapping strategies. In addition I propose to determine the routes and importance of alanine and asparagine synthesis as well as GABA catabolism to amino acid cycling.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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