Award details

Vitamin D and the immune system

ReferenceBBS/B/01014
Principal Investigator / Supervisor Dr David Lammas
Co-Investigators /
Co-Supervisors
Professor David Sansom
Institution University of Birmingham
DepartmentMedical Sciences - Medicine
Funding typeResearch
Value (£) 307,889
StatusCompleted
TypeResearch Grant
Start date 01/04/2004
End date 31/10/2007
Duration43 months

Abstract

Recent studies have implicated vitamin D in human health issues beyond its classical effects on bone and calcium. This includes: 1) epidemiology linking vitamin D deficiency with immune disorders and common cancers; 2) experimental data highlighting the antiproliferative/immunomodulatory effect of the active form of vitamin D. The aim of the proposed project is to link these two sets of observations by testing the hypothesis that vitamin D is a potent regulator of normal immune responses. Using in vitro and in vivo models to assess the effects of vitamin D-supplementation on different aspects of immune function, the project will seek to define a role for vitamin D as a key dietary factor in the prevention of immune disorders.

Summary

unavailable
Committee Closed Committee - Agri-food (AF)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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