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What are the barriers to animal-animal and animal-human species jumps by paramyxo- and pneumoviruses?

ReferenceBBS/B/0062X
Principal Investigator / Supervisor Professor Thomas Barrett
Co-Investigators /
Co-Supervisors		 Dr Michael Baron
Institution The Pirbright Institute
DepartmentDiv of Microbiology Pirbright
Funding typeResearch
Value (£) 320,370
StatusCompleted
TypeResearch Grant
Start date 01/10/2004
End date 31/03/2008
Duration42 months

Abstract

This application aims to consolidate informal collaborations between four groups that already share a common interest in the pathology of viral diseases of livestock and have exchanged reagents in the past. A strong theme that links the groups is an interest in global threat from exotic viruses. The work aims to gain a better understanding of pathophysiology of host-pathogen interactions and persistent infections and transmission, as well as improving vaccinology for the paramyxovirus family of viruses. The focus of this application is the `Barriers to cross-species infection, in particular the interaction of virus with their natural hosts and with species in which they have the potential to emerge. This work is of relevance to an understanding not only of cross-species infection between animals but also zoonotic infections such as the recently emerged SARS coronavirus.

Summary

unavailable
Committee Closed Committee - Animal Sciences (AS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative Combating Viral Diseases of Livestock Initiative (CVDL) [2003]
Funding SchemeX – not Funded via a specific Funding Scheme
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