Award details

Structural study of doublecortin: a microtubule bundling protein essential for neuronal migration

ReferenceBBS/A/00048
Principal Investigator / Supervisor Professor Carolyn Moores
Co-Investigators /
Co-Supervisors
Institution Birkbeck College
DepartmentBiological Sciences
Funding typeResearch
Value (£) 414,863
StatusCompleted
TypeFellowships
Start date 01/01/2004
End date 31/12/2008
Duration60 months

Abstract

The proposed research programme addresses the BBSRCs mission is seeking to characterise structurally the novel mechanism of interaction between doublecortin and microtubules using state-of-the-art techniques. This will provide insight into the ways in which the microtubule cytoskeleton is regulated, particularly in motile neurones during brain development. The methods developed during this structural project will be generally applicable to other cytoskeletal arrays.

Summary

unavailable
Committee Closed Committee - Biomolecular Sciences (BMS)
Research TopicsNeuroscience and Behaviour, Structural Biology
Research PriorityX – Research Priority information not available
Research Initiative Fellowship - David Phillips Fellowship (DF) [1995-2015]
Funding SchemeX – not Funded via a specific Funding Scheme
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