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Phylodynamics: synthesising the population dynamics and phylogenetics of animal pathogens
Reference
BBS/A/0003X
Principal Investigator / Supervisor
Professor Bryan Grenfell
Co-Investigators /
Co-Supervisors
Institution
University of Cambridge
Department
Zoology
Funding type
Research
Value (£)
499,042
Status
Completed
Type
Fellowships
Start date
01/10/2003
End date
30/09/2004
Duration
12 months
Abstract
(a) Develop a family of models relating pathogen strain structure of epidemic dynamics in Equine Influenza (EI), spanning levels from within-host to population, based on experimentally quantifying: (i) within-host strain dynamics (by genotyping of longitudinal viral samples); (ii) impact of transmission founder effects on viral genetic diversity. (b) Apply the models to understand dynamics of EIV phylogeny, notably, drift and co-circulation of strains. (c) Generalise the EI model to explore strain dynamics of other pathogens: (i) rabies; (ii) Foot and Mouth Disease.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Fellowship - Professorial Fellowship (PF) [1996-2009]
Funding Scheme
X – not Funded via a specific Funding Scheme
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