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The PPP-labels software for quantitative proteomics

Reference	BB/L024462/1
Principal Investigator / Supervisor	Professor Andrew Jones
Co-Investigators / Co-Supervisors	Professor Robert Beynon, Professor Claire Eyers
Institution	University of Liverpool
Department	Institute of Integrative Biology
Funding type	Research
Value (£)	125,876
Status	Completed
Type	Research Grant
Start date	30/09/2014
End date	29/09/2015
Duration	12 months

Abstract

unavailable

Summary

The large-scale study of proteins (the functional molecules in cells) is called proteomics and the main technology for identification and quantification is mass spectrometry (MS). There are two popular proteomics methods, called "label-based" and "label-free". One of the leading commercial software packages for label-free data analysis is Progenesis LC-MS from Nonlinear Dynamics (Newcastle, UK). We previously developed an application for adapting Progenesis LC-MS to analyse data from label-based studies, called the Progenesis Post-Processor (PPP). In this project, we are in the process of commercialising this software in a product called PPP-labels. We have requested support in the lead up to the release of the first version on the open market. We are also going to generate data sets in which we know the abundance of proteins to demonstrate and benchmark PPP-labels.

Committee	Not funded via Committee
Research Topics	Technology and Methods Development
Research Priority	X – Research Priority information not available
Research Initiative	Follow-On Fund (FOF) [2004-2015]
Funding Scheme	X – not Funded via a specific Funding Scheme

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