Award details

Development of new generation of growth factors for regenerative medicine

Reference	BB/P023681/1
Principal Investigator / Supervisor	Professor Marko Hyvonen
Co-Investigators / Co-Supervisors
Institution	University of Cambridge
Department	Biochemistry
Funding type	Research
Value (£)	412,877
Status	Completed
Type	Research Grant
Start date	16/06/2017
End date	30/11/2019
Duration	29 months

Abstract

unavailable

Summary

Regenerative medicine is one of the most important emerging fields in modern medicine. It aims to replace, engineer or regenerate human cells, tissues or organs to restore their normal function. An example of such treatment would be restoration of pancreatic beta cells to reverse insulin deficiency in diabetic patients. A key aspect of the processes needed to restore or regenerate tissues is to use specific growth factors or hormones to drive the cells in the desired direction to restore the lost structure or function. We aim to develop safer, more efficient and more specific growth factors for use in regenerative medicine. We will achieve this by characterising our growth factors extensively using number of different criteria, to ensure they are suitable for clinical use. We will also use protein engineering to develop next generation growth factors with improved properties to allow researchers to fine-tune the responses of cells and help research efforts in new and emerging areas.

Committee	Not funded via Committee
Research Topics	Regenerative Biology, Stem Cells
Research Priority	X – Research Priority information not available
Research Initiative	Follow-On Fund Super (SuperFOF) [2012-2015]
Funding Scheme	X – not Funded via a specific Funding Scheme

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