Award details

Development of NanoKick Bioreactor

Reference	BB/N012690/1
Principal Investigator / Supervisor	Professor Matthew Dalby
Co-Investigators / Co-Supervisors	Professor S. Faisal Ahmed, Mr Kenny Cameron, Professor Stuart Reid
Institution	University of Glasgow
Department	College of Medical, Veterinary, Life Sci
Funding type	Research
Value (£)	196,771
Status	Completed
Type	Research Grant
Start date	15/02/2016
End date	14/02/2017
Duration	12 months

Abstract

unavailable

Summary

Bone graft is the most transplanted tissue after blood. It is in short supply and demand is increasing with the aging population. Taking graft from a patient to transplant back to the patient is possible but results in morbidity of the donor site (normally the pelvis). We have developed a novel bioreactor, called Nanokick, which can be used to efficiently and effectively convert mesenchymal stem cells (MSCs - the bones natural stem cell supply) into osteoblasts (bone building cells). It works by supplying tiny kicks to cells. Our approach will provide technology that enables provision of 3D living bone derived from a patients own cells that produces effective repair. Areas this would be useful would include all bone reconstructions, spinal fusion and joint replacement. These in no need for chemicals and associated side effects (e.g. widely used bone morphogenic protein is now associated with adverse effects). In this work we will develop our technology towards a commercial product.

Committee	Not funded via Committee
Research Topics	Pharmaceuticals, Regenerative Biology
Research Priority	X – Research Priority information not available
Research Initiative	Follow-On Fund (FOF) [2004-2015]
Funding Scheme	X – not Funded via a specific Funding Scheme

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