Award details

Development of a low cost arsenate sensor

Reference	BB/N012674/1
Principal Investigator / Supervisor	Professor Joanne Santini
Co-Investigators / Co-Supervisors	Professor Anthony Cass
Institution	University College London
Department	Structural Molecular Biology
Funding type	Research
Value (£)	192,691
Status	Completed
Type	Research Grant
Start date	01/04/2016
End date	31/03/2018
Duration	24 months

Abstract

unavailable

Summary

Arsenic is an infamous toxin and the WHO has labelled drinking arsenic-contaminated water by hundreds of millions of people "The greatest mass poisoning of a population in human history". While arsenic remediation remains the answer to this problem, it needs to be combined with a quick, low-cost, simple to use and accurate method of determining the amount of both species of soluble arsenic in water. In the short term, this is essential to prevent people drinking water laden with arsenic and then to identify sources that need remediation and to confirm its effectiveness. In this project we will expand our arsenic sensor technology from detecting only one (the most toxic) of the two forms of soluble arsenic to both. Together with arsenite oxidase to measure arsenite concentrations we will develop an enzyme-electrochemical arsenate sensor using the enzyme arsenate reductase. Together the two enzymes will form the basis of this novel sensing system measuring both forms on a single strip.

Committee	Not funded via Committee
Research Topics	Microbiology
Research Priority	X – Research Priority information not available
Research Initiative	Follow-On Fund (FOF) [2004-2015]
Funding Scheme	X – not Funded via a specific Funding Scheme

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