Award details

An integrated upper GI model of digestion and absorption - the commercial 'Holy Grail'

ReferenceBB/N012666/1
Principal Investigator / Supervisor Professor Jeff Pearson
Co-Investigators /
Co-Supervisors
Institution Newcastle University
DepartmentInst for Cell and Molecular Biosciences
Funding typeResearch
Value (£) 152,719
StatusCompleted
TypeResearch Grant
Start date 01/04/2016
End date 30/09/2017
Duration18 months

Abstract

unavailable

Summary

Modelling the processes of digestion, nutrient uptake and drug absorption in the laboratory reduces the need to carry out expensive and controversial studies in animals and humans. We aim to develop a fully integrated lab model of digestion and absorption to screen and develop new drugs and health interventions. The commercial need in the pharmaceutical industry for this model has been identified during a BBSRC Enterprise Fellowship and validated through independent market research funded by a BBSRC Pathfinder award, and we have applied for a patent of this technology. This integrated model has been described as the 'Holy Grail' and would allow food and pharmaceutical companies to carry out affordable screening and development studies to inform product development and drug discovery. This would significantly reduce the high costs of drug development. Furthermore an effective, validated model of digestion would reduce the need for a great number of animal studies.
Committee Not funded via Committee
Research TopicsDiet and Health, Pharmaceuticals, Systems Biology, The 3 Rs (Replacement, Reduction and Refinement of animals in research)
Research PriorityX – Research Priority information not available
Research Initiative Follow-On Fund (FOF) [2004-2015]
Funding SchemeX – not Funded via a specific Funding Scheme
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