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Award details
An integrated upper GI model of digestion and absorption - the commercial 'Holy Grail'
Reference
BB/N012666/1
Principal Investigator / Supervisor
Professor Jeff Pearson
Co-Investigators /
Co-Supervisors
Institution
Newcastle University
Department
Inst for Cell and Molecular Biosciences
Funding type
Research
Value (£)
152,719
Status
Completed
Type
Research Grant
Start date
01/04/2016
End date
30/09/2017
Duration
18 months
Abstract
unavailable
Summary
Modelling the processes of digestion, nutrient uptake and drug absorption in the laboratory reduces the need to carry out expensive and controversial studies in animals and humans. We aim to develop a fully integrated lab model of digestion and absorption to screen and develop new drugs and health interventions. The commercial need in the pharmaceutical industry for this model has been identified during a BBSRC Enterprise Fellowship and validated through independent market research funded by a BBSRC Pathfinder award, and we have applied for a patent of this technology. This integrated model has been described as the 'Holy Grail' and would allow food and pharmaceutical companies to carry out affordable screening and development studies to inform product development and drug discovery. This would significantly reduce the high costs of drug development. Furthermore an effective, validated model of digestion would reduce the need for a great number of animal studies.
Committee
Not funded via Committee
Research Topics
Diet and Health, Pharmaceuticals, Systems Biology, The 3 Rs (Replacement, Reduction and Refinement of animals in research)
Research Priority
X – Research Priority information not available
Research Initiative
Follow-On Fund (FOF) [2004-2015]
Funding Scheme
X – not Funded via a specific Funding Scheme
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