Award details

Thermosensory processing: mechanisms and pathways

Reference	BB/H016597/1
Principal Investigator / Supervisor	Professor Anthony Dickenson
Co-Investigators / Co-Supervisors	Dr Nicola Brice
Institution	University College London
Department	Neuroscience Physiology and Pharmacology
Funding type	Skills
Value (£)	83,281
Status	Completed
Type	Training Grants
Start date	01/10/2010
End date	30/09/2014
Duration	48 months

Abstract

unavailable

Summary

The application will support basic research in the area of sensory neuroscience and will focus on the mechanisms of thermal coding using a wide range of approaches that include in vivo electrophysiology, behavioural phenotyping, molecular biology, cell biology including culturing and measuring cell markers from primary cultures. The aim is to use a wide range of integrated techniques that will allow a comprehensive understanding of how thermal information is transduced and transmitted to the central nervous system. This will be studied in the normal state but also will allow the study of molecular and neuronal plasticity since abnormal perceptual changes to cooling stimuli are observed in neuropathic pain patients and the same is true for animal models of nerve injury.

Committee	Not funded via Committee
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	Training Grant - Industrial Case

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