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Award details
Host serum biomarkers for diagnosing bovine TB. Towards a point-of-care test.
Reference
BB/E527247/1
Principal Investigator / Supervisor
Professor Paul Langford
Co-Investigators /
Co-Supervisors
Institution
Imperial College London
Department
Dept of Medicine
Funding type
Research
Value (£)
89,841
Status
Completed
Type
Research Grant
Start date
01/05/2007
End date
30/04/2008
Duration
12 months
Abstract
unavailable
Summary
There is an urgent need for new simple rapid cheap diagnostic method for bovine TB. In a pilot study, funded by the BBSRC, we have found 7 serum protein biomarkers that discriminate between culture positive proven cases of bovine TB from non-infected animals. Two markers have been identified at the molecular level. We propose (1) to validate these 2 markers using an immunologically based test on a separate cohort of TB-infected and non-infected animals and (2) identify the remaining 5 biomarkers at the molecular level and also validate them. The data will be used to formulate a simple point-of-care (POC test) for bovine TB.
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
Animal Health
Research Priority
X – Research Priority information not available
Research Initiative
Follow-On Fund (FOF) [2004-2015]
Funding Scheme
X – not Funded via a specific Funding Scheme
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