Award details

Novel targets for vaccine development and immunotherapy to combat Staphylococcus aureus and other pathogens

Reference	BB/D525748/1
Principal Investigator / Supervisor	Professor Simon J. Foster
Co-Investigators / Co-Supervisors
Institution	University of Sheffield
Department	Molecular Biology and Biotechnology
Funding type	Research
Value (£)	59,703
Status	Completed
Type	Research Grant
Start date	01/04/2006
End date	31/03/2007
Duration	12 months

Abstract

Antibiotic resistant, pathogenic bacteria are a constant and increasing threat. An important alternative to antibiotics is disease prevention by vaccination and the use of therapeutic antibodies. The project will develop a new class of vaccine/antibody targets against the superbug Staphylococcus aureus and other infectious microbes. The targets are those which are essential for the life of the cell and so the bacterium cannot do without them. Our BBSRC funded work has identified suitable novel targets in S. aureus and has shown them to be accessible to the immune system. A patent has been filed by the University of Sheffield to protect this finding. For further exploitation and commercialisation the essential components need to be produced and their potential as vaccine constituents examined. Concomitant with scientific advances a commercial structure will be established to allow the full potential of the area to be realised.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Follow-On Fund (FOF) [2004-2015]
Funding Scheme	X – not Funded via a specific Funding Scheme

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