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2D-NAAT: A universal handheld assay platform for ultra-sensitive low-cost biological detection.
Reference
BB/C519262/1
Principal Investigator / Supervisor
Dr Laurence Tisi
Co-Investigators /
Co-Supervisors
Institution
Lumora Ltd
Department
Lumora Ltd
Funding type
Research
Value (£)
232,965
Status
Completed
Type
Research Grant
Start date
01/07/2005
End date
30/06/2008
Duration
36 months
Abstract
There is an urgent need for a new generation of cost-effective approaches to take highly sensitive assays based on nucleic acid amplification tests (NAAT) from the laboratory into truly handheld devices. Here we propose to develop the 2D-NAAT: an extension of the strip assay concept, in which the sample is first separated and purified by a wicking process, and the target is then amplified at a constant temperature and detected by using proprietary technology that visualises ongoing amplification by real-time light output. This will provide a revolutionary new generic platform for both DNA and highly sensitive immuno-assays combining a small, cheap detection device with disposable plastic cassettes for a wide range of biological analytes.
Summary
unavailable
Committee
Closed Committee - Engineering & Biological Systems (EBS)
Research Topics
Technology and Methods Development
Research Priority
X – Research Priority information not available
Research Initiative
Small Business Research Initiative (SBRI) [2001-2005]
Funding Scheme
X – not Funded via a specific Funding Scheme
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