Award details

Integration of leaf metabolism and physiology by the trehalose pathway

Reference	BB/C512645/1
Principal Investigator / Supervisor	Dr Astrid Wingler
Co-Investigators / Co-Supervisors
Institution	University College London
Department	Genetics Evolution and Environment
Funding type	Research
Value (£)	71,402
Status	Completed
Type	Research Grant
Start date	01/07/2005
End date	30/06/2008
Duration	36 months

Abstract

The discovery of the trehalose pathway as a central and indispensable regulatory system in plants is a major finding in the study of metabolic regulation in recent years. Research on transgenic and mutant plants has shown that there is an obligate requirement for the trehalose pathway and the metabolite trehalose 6-phosphate (T6P), in particular for carbohydrate utilisation. An important consequence of altered T6P-dependent metabolism in leaves is an impact on photosynthesis: transgenic plants with elevated T6P content show a large increase in photosynthetic capacity per unit leaf area. Furthermore, modification of T6P content causes predictable changes in carbohydrate and photosynthetic metabolism and in leaf development showing that these three processes are linked through T6P. New data show crosstalk between T6P and SnRK1. the proposal seeks to investigate this crucial role of T6P in integrating leaf physiology using transgenic and mutant Arabidopsis with perturbed T6P metabolism and perturbed SnRK1 activity focusing on: 1) The molecular and biochemical base of T6P-dependent changes in metabolism and leaf development; 2) regulation of T6P metabolism by native Arabidopsis genes and their role in the integration of leaf physiology. Join with BB/C51257X/1.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	Plant Science
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

Associated awards:

BB/C51257X/1 Integration of leaf metabolism and physiology by the trehalose pathway

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