Award details

A tandem mass spectrometer for microbial proteomics

Reference	BB/C510940/1
Principal Investigator / Supervisor	Professor Al Brown
Co-Investigators / Co-Supervisors	Professor Ian Booth, Dr Phillip Cash, Professor James I Prosser, Professor Margaret Smith
Institution	University of Aberdeen
Department	Institute of Medical Sciences
Funding type	Research
Value (£)	183,824
Status	Completed
Type	Research Grant
Start date	01/12/2004
End date	31/01/2006
Duration	14 months

Abstract

The objective of this proposal is to provide Tandem LC/MS facilities for the Proteomics Facility at Aberdeen University. This will significantly increase the capabilities of this core facility, which has a proud record of providing a high quality proteomics service to local and external users for many years. The Aberdeen Proteomics Facility provides a range of services including 2D-gel electrophoresis, robotic spot cutting and processing, peptide mass fingerprinting using a MALDI-ToF mass spectrometer, protein (micro)sequencing and peptide synthesis. The addition of Tandem LC/MS-MS will open the door to high resolution proteomic technologies that will be exploited by a range of Microbial Proteomics Research Groups at Aberdeen University. These well-funded and productive groups are studying the proteomes of fungal and bacterial pathogens, the post-translational modification of bacterial and bacteriophage proteins, and the proteomes of environmentally important ammonia oxidising bacteria. In addition the Tandem LC/MS-MS will be exploited by a range of other research groups working in Molecular Medicine. This Tandem LC/MS-MS will strengthen the infrastructure of the Aberdeen Proteomics Facility significantly, and hence will accelerate the proteomics work undertaken by research groups at Aberdeen University. In addition, it will enhance the services provided to external users by the Aberdeen Proteomics Facility and the COGEME Proteomics Facility 1.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Research Equipment Initiative 2004 (RE4) [2004]
Funding Scheme	X – not Funded via a specific Funding Scheme

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