Award details

Intrinsic anatomical connections within cortical area V5/MT and their significance for perceptual processing.

Reference	BB/C504943/1
Principal Investigator / Supervisor	Professor Kristine Krug
Co-Investigators / Co-Supervisors	Dr Wyeth Bair, Professor Andrew John Parker
Institution	University of Oxford
Department	Physiology Anatomy and Genetics
Funding type	Research
Value (£)	394,233
Status	Completed
Type	Research Grant
Start date	01/01/2005
End date	30/09/2008
Duration	45 months

Abstract

The extrastriate visual area V5/MT has been identified as an important site for visual perception. Neurons in V5/MT of the awake, behaving primate do not respond simply to the motion or binocular depth of external visual stimuli but also reflect the perceptual decisions made by the animal about these stimuli. Studies of this brain region with an ambiguous rotating cylinder (defined by structure from motion) have been particularly revealing. Although studies of V5/MT have been fundamental in identifying principles of how neuronal activity is linked to visual behaviour, surprisingly little is known about the intrinsic anatomy of the cortical region. This project will study the patterns of horizontal interconnections in macaque monkeys. The physiological measurements at each site will identify the preferred direction of motion and the binocular depth sensitivity of the neurons so that the specificity of the horizontal interconnections can be assessed. At the same time, we will measure the interneuronal correlations between cortical sites according to both their stimulus specificity and their response to the ambiguous visual stimuli that have been used to study perceptual decision making in this brain region. Finally we will assemble the results into a computational model of the response of this brain region to ambiguous visual figures.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	Neuroscience and Behaviour
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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