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BBSRC David Phillips Fellowship: Spatiotemporal properties of Ca 2+ signalling pathways in cerebellar astrocytes
Reference
BB/B500958/1
Principal Investigator / Supervisor
Dr Tomas Bellamy
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Molecular Signalling
Funding type
Research
Value (£)
345,937
Status
Completed
Type
Fellowships
Start date
01/11/2004
End date
31/10/2009
Duration
60 months
Abstract
In the cerebellar cortex, synaptic activity can generate Ca2+ signals in extrasynaptic glia through three different pathways. The main aims of the proposed work are: to determine how the spatiotemporal properties of glial Ca2+ signals evoked during synaptic transmission are related to the frequency and strength of presynaptic stimulation: to determine the mechanism by which the nitric oxide pathway is linked to Ca2+ elevation; and to investigate the impact of glial Ca2+ signalling, evoked by the various pathways, on the function of the cerebellar circuit.
Summary
unavailable
Committee
Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics
Neuroscience and Behaviour
Research Priority
X – Research Priority information not available
Research Initiative
Fellowship - David Phillips Fellowship (DF) [1995-2015]
Funding Scheme
X – not Funded via a specific Funding Scheme
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