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Probing the relative efficiences of direct and reciprocal replication strategies

Reference	B20102
Principal Investigator / Supervisor	Professor Douglas Philp
Co-Investigators / Co-Supervisors
Institution	University of St Andrews
Department	Biology
Funding type	Research
Value (£)	188,535
Status	Completed
Type	Research Grant
Start date	01/01/2004
End date	31/12/2006
Duration	36 months

Abstract

This project will examine the relationship between the two simplest models of molecular replication ¿ the direct or minimal model and the more complex double cross-catalytic or reciprocal model. Whilst the direct model is more atom-efficient, the reciprocal model is more robust in terms of information storage and stability. The basic objective of this research is to address the fundamental question Why and how did reciprocal replicating systems emerge? This question is fundamental to understanding the transition from prebiotic chemical world to the first self-reproducing systems. We will employ two strategies to answer this question involving isolation and exclusion of the possible replicating models.

Summary

unavailable

Committee	Closed Committee - Biomolecular Sciences (BMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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