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Controlling vesicular adhesion for applications in bio- and nanotechnology
Reference
B19722
Principal Investigator / Supervisor
Professor Simon Webb
Co-Investigators /
Co-Supervisors
Institution
The University of Manchester
Department
Chemistry
Funding type
Research
Value (£)
138,917
Status
Completed
Type
Research Grant
Start date
19/01/2004
End date
18/01/2006
Duration
24 months
Abstract
We will use synthetic receptors embedded in the membranes of vesicles, simple cell mimics, to model the way cell adhesion molecules control the adhesive properties of cells, the mechanism of which has only recently been elucidated. Recent advances in biomimetic chemistry makes this the ideal time to use synthetic models to investigate the role molecular interactions play in organising receptors within membranes, and how this determines the adhesive properties of entire cells. To control the strength and direction of adhesion we will copy nature and control the distribution of receptors over the membrane surface. The vesicular structures formed will give a better understanding of tissue function and have applications in nanotechnology.
Summary
unavailable
Committee
Closed Committee - Biomolecular Sciences (BMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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