Award details

Automated high throughput systems for the production of recombinant baculovirus expression vectors

Reference	B19427
Principal Investigator / Supervisor	Professor Linda King
Co-Investigators / Co-Supervisors	Professor Robert Possee
Institution	Oxford Brookes University
Department	Faculty of Health and Life Sciences
Funding type	Research
Value (£)	192,144
Status	Completed
Type	Research Grant
Start date	01/06/2003
End date	30/09/2006
Duration	40 months

Abstract

In the post-genomic era there is a requirement for the high throughput production of recombinant proteins for a variety of purposes including expression analysis of sequenced genomes and structure-function analysis of medically important proteins. To date automated high throughput expression systems have been limited to those systems using bacterial cells. Although this serves the requirements for some proteins, many require a eukaryotic host cell to produce authentic proteins. In this project we aim to develop for the first time, an automated high throughput system for the production of recombinant proteins in insect (eukaryotic) cells using novel baculovirus expression vectors.

Summary

unavailable

Committee	Closed Committee - Biomolecular Sciences (BMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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