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Determining the macromolecular structure of the light harvesting supercomplexes of plants green algae and cyanobacteria

Reference	B17945
Principal Investigator / Supervisor	Professor James Barber
Co-Investigators / Co-Supervisors	Dr Edward Morris
Institution	Imperial College London
Department	Biological Sciences
Funding type	Research
Value (£)	262,784
Status	Completed
Type	Research Grant
Start date	15/02/2003
End date	14/01/2007
Duration	47 months

Abstract

The structure of macromolecular supercomplexes from plants, green algae and cyanobacteria will be determined using high resolution electron cryomicroscopy to obtain a molecular framework in which to model structures at atomic resolution derived from X-ray crystallography. Both electron crystallography and single particle analyses will be employed. In vivo and in vitro 2D crystals will be used to obtain the 3D structure of the plant or green algal LHCII-PSII supercomplex at a resolution of 8 angstrom or better while single particle analyses will be exploited to obtain the 3D structure of the allophycocyanin-PSII supercomplex of cyanobacteria. In this way an understanding of how the light harvesting systems of photosystem II transfer energy to the reaction centre will be elucidated and extended to the in vivo system.

Summary

unavailable

Committee	Closed Committee - Biomolecular Sciences (BMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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