Award details

Oxford Centre for Molecular Sciences

Reference	B16674
Principal Investigator / Supervisor	Professor Iain Campbell
Co-Investigators / Co-Supervisors	Sir J Baldwin, Professor Stephen Fuller, Professor Dame Louise Johnson, Professor Yvonne Jones, Professor Martin Noble, Professor Christopher Joseph Schofield
Institution	University of Oxford
Department	Biochemistry
Funding type	Research
Value (£)	1,987,840
Status	Completed
Type	Research Grant
Start date	01/01/2002
End date	31/12/2005
Duration	48 months

Abstract

OCMS has become established as a leading research institution in protein science. In the next 5 years it will continue to provide an interdisciplinary link between chemistry, biochemistry, and medicine, using X-ray crystallography, NMR electron microscopy and other biophysical methods as the central tools. Our goal is to combine these tools in a concerted effort to understand the nature of some large protein assemblies. In particular we will investigate i) enzyme complexes in secondary metabolism ii) extracellular receptor complexes and iii) intracellular signalling complexes. The aim is to provide an atomic resolution structural framework for understanding catalytic mechanisms and dynamic interactions in these systems. In recognition of scientific advances and the changed funding climate since 1988, a new management structure will be introduced.

Summary

unavailable

Committee	Closed Committee - Biomolecular Sciences (BMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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