Award details

NW Structure Genomics Centre's high-throughput MAD beamline for pathogen genomes

Reference	B15474
Principal Investigator / Supervisor	Professor Samar Hasnain
Co-Investigators / Co-Supervisors	Professor John R Helliwell
Institution	STFC - Laboratories
Department	Photon Science
Funding type	Research
Value (£)	2,600,000
Status	Completed
Type	Research Grant
Start date	01/08/2001
End date	01/08/2006
Duration	60 months

Abstract

This award will support a NW Structure Genomics Centre (NWSGC) to exploit the strength of ten groups from a number of NW Universities, a major pharmaceutical industry (AstraZeneca) and Daresbury Laboratory as well as the unique resource offered by the close proximity to the only synchrotron radiation source in the UK. The aim is to develop the infrastructure and facilities at the Laboratory to support a high-throughput crystallographic structure determination of proteins in a number of pathogens with the ultimate aim of improving our understanding of host- pathogen interactions leading to more effective drugs. This will provide a world competitive MAD facility in the UK. The facility will also underpin research grant applications to build the following high throughput facilities at Daresbury as part of a high-throughput structure genomics effort: (i) a protein production factory and (ii) a robotic based crystallisation laboratory.

Summary

unavailable

Committee	Closed Committee - Biomolecular Sciences (BMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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