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Award details
Utilising direct methods and accurate synchrotron radiation data for solving macromolecular crystal structures
Reference
B08494
Principal Investigator / Supervisor
Professor Keith Wilson
Co-Investigators /
Co-Supervisors
Institution
University of York
Department
Chemistry
Funding type
Research
Value (£)
172,576
Status
Completed
Type
Research Grant
Start date
01/02/1998
End date
01/02/2001
Duration
36 months
Abstract
Direct Methods revolutionised small molecule crystallography in the 1970s. Until recently macromolecules have presented an intractable challenge to such approaches, but there is a pressing need today to provide macromolecular structure solutions as quickly and automatically as possible, owing to the vast number of important proteins becoming available inter alia through the sequence of whole genomes. Direct Methods are presently poised to make a significant contribution here. This proposal combines the expertise of theoreticians and experimentalists, especially exploiting either atomic resolution of MAD data from synchrotron radiation (SR).
Summary
unavailable
Committee
Closed Committee - Biomolecular Sciences (BMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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