Award details

Computational support for partition-based compound selection

ReferenceB07391
Principal Investigator / Supervisor Professor Peter Willett
Co-Investigators /
Co-Supervisors
Institution University of Sheffield
DepartmentInformation Studies
Funding typeResearch
Value (£) 113,377
StatusCompleted
TypeResearch Grant
Start date 01/02/1997
End date 31/01/2000
Duration36 months

Abstract

Combinatorial approaches to the design of novel bioactive compounds require sets of structurally disparate reagents. This project will develop effective and efficient computer techniques for the selection of such sets from available chemical databases, using a technique known as partition-based compound selection. Areas to be investigated include the specification of the bins comprising a partition, the calculation of the physical properties defining the partition, and the choice of compound from the resulting bins.

Summary

unavailable
Committee Closed Committee - Biomolecular Sciences (BMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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