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Structure determination of photosynthetic proteins by high resolution electron microscopy

Reference	B06793
Principal Investigator / Supervisor	Professor Per Bullough
Co-Investigators / Co-Supervisors
Institution	University of Sheffield
Department	Molecular Biology and Biotechnology
Funding type	Research
Value (£)	37,671
Status	Completed
Type	Research Grant
Start date	25/10/1996
End date	25/10/1999
Duration	36 months

Abstract

We request funds for consumables, and a contribution to travel for the structure determination of bacterial photosynthetic proteins by high resolution electron microscopy. We will determine the 3D structure of the light harvesting complex LH1 at high resolution, continuing on from our current projection structure. We will investigate complexes of other proteins involved in photosynthesis by 2D and 3D crystallisation. This should prepare us for structure determinations most likely by electron microscopy but possibly also by X-ray crystallography. This work will lead to an improved understanding of membrane protein assembly in general and the specific structure/function relationships of some important energy transducing proteins.

Summary

unavailable

Committee	Closed Committee - Biomolecular Sciences (BMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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