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Bioactive ion sensors with luminescent signal transduction

ReferenceB05911
Principal Investigator / Supervisor Professor David Parker
Co-Investigators /
Co-Supervisors
Institution Durham University
DepartmentChemistry
Funding typeResearch
Value (£) 131,738
StatusCompleted
TypeResearch Grant
Start date 01/10/1996
End date 30/09/1999
Duration36 months

Abstract

The development of phosphorescent sensing systems for the detection, quantification and monitoring of bioactive cations and molecules in cells or in biological fluids. The luminescent sensors involve (a) the coupling of a strongly emissive lanthanide complex with a selective receptor for the binding of Cl-, Zn2+, Trp and Tyr. (b) the study of responsive ligands for Na+ (or Li+) where ligand regulation following ion binding switches an excimer emission.

Summary

unavailable
Committee Closed Committee - Biomolecular Sciences (BMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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