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Award details
Establishment of a stopped flow facility
Reference
B05046
Principal Investigator / Supervisor
Professor Nicholas Price
Co-Investigators /
Co-Supervisors
Institution
University of Stirling
Department
Biological and Environmental Sciences
Funding type
Research
Value (£)
61,909
Status
Completed
Type
Research Grant
Start date
04/12/1995
End date
04/12/1997
Duration
24 months
Abstract
Funding is requested to establish a stopped flow facility capable of recording in absorbance, fluorescence and circular dichroism (c.d.) modes. This will be used to provide kinetic insights into the key biological processes of protein folding and assembly and macromolecule/ligand interaction. Four systems (which are ideal for this work) have been chosen to illustrate these themes:- (1) The folding of the monomeric phosphoglycerate mutase from Schizosaccharomyces pombe, (2) The folding and assembly of the type II dehydroquinase from Streptomyces coelicolor, (3) The folding and reactivation of BM3 cytochrome P450 from Bacillus megaterium, and (4) The interaction between DNA methyltransferases and their cognate DNAs.
Summary
unavailable
Committee
Closed Committee - Biomolecular Sciences (BMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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