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Kinetic studies of the folding and assembly of membrane proteins
Reference
B04222
Principal Investigator / Supervisor
Professor Paula Booth
Co-Investigators /
Co-Supervisors
Professor Sabine Flitsch
Institution
Imperial College London
Department
Biological Sciences
Funding type
Research
Value (£)
5,427
Status
Completed
Type
Research Grant
Start date
01/10/1994
End date
01/10/1997
Duration
36 months
Abstract
1. Detailed investigation of the kinetics of membrane protein folding using bacteriorhodopsin as a model system. 2. Study of bacteriorhodopsin mutant proteins to determine the role of specific amino acid sidechains in the assembly process. 3. Detailed investigation of the role which Arg175 plays in bacteriorhodospin folding, especially in helix orientation and interactions with lipid head groups.
Summary
unavailable
Committee
Closed Committee - Biomolecular Sciences (BMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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