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Mechanism of quinolinate phosphoribosyltransferase
Reference
B04220
Principal Investigator / Supervisor
Dr Nigel Botting
Co-Investigators /
Co-Supervisors
Institution
University of St Andrews
Department
Biology
Funding type
Research
Value (£)
6,000
Status
Completed
Type
Research Grant
Start date
01/10/1994
End date
01/10/1997
Duration
36 months
Abstract
1. Determination of kinetic importance and relative order of decarboxylation and phosphoribosyl transfer steps. Measurement of kinetic isotope effects. 2. Comparison with mechanism of the uncatalysed reaction. 3. Synthesis of photoaffinity labels and use to obtain FIRST structural information on QPRTase.
Summary
unavailable
Committee
Closed Committee - Biomolecular Sciences (BMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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