Award details

Investigation of the mechanism of PS2 electron transfer

Reference	B04049
Principal Investigator / Supervisor	Professor J Nugent
Co-Investigators / Co-Supervisors	Dr Patrick OMalley, Dr Stephen Rigby
Institution	University College London
Department	Genetics Evolution and Environment
Funding type	Research
Value (£)	203,589
Status	Completed
Type	Research Grant
Start date	01/08/1995
End date	30/09/1998
Duration	38 months

Abstract

Our overall aim is to understand the pathway and mechanism of electron transfer in photosystem 2 (PS2), a photosynthetic membrane-protein complex found in plants, algae and cyanobacteria. It is responsible through water oxidation for most of our oxygen atmosphere and is an important part of the biological solar energy conversion system. In previous work, key amino acid sites in the core complex were predicted by molecular modelling and specific mutants constructed in several laboratories. We will now investigate these by spectroscopic techniques and compare them to the native state which we have characterised. This project will give fine structural information on cofactor positions, H-bonding, electron spin density of cofactors and how their redox properties are controlled. Together these will provide a model of electron transfer through PS2, a crucial aid to future experiments to mimic or modify photosynthetic systems.

Summary

unavailable

Committee	Closed Committee - Biomolecular Sciences (BMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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