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Determination of structure transketolase from Escherichia coli studies with site-directed mutants and analogues
Reference
B03639
Principal Investigator / Supervisor
Professor Jennifer Littlechild
Co-Investigators /
Co-Supervisors
Professor Nicholas Turner
Institution
University of Exeter
Department
Chemistry
Funding type
Research
Value (£)
197,746
Status
Completed
Type
Research Grant
Start date
01/03/1994
End date
01/09/1997
Duration
42 months
Abstract
1. Structure of E. coli transketolase (TK) using yeast tranketolase co-ordinates. 2. Refinement of E. coli TK structure. Extension of resolution of data using Synchrotron radiation. 3. Crystallisation of E. coli TK with substrates of interest for biotransformation. 4. Crystallisation and structure determination of mutants and redesigned enzyme.
Summary
unavailable
Committee
Closed Committee - Biomolecular Sciences (BMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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