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Mechanistic studies on type I and type II dehydroquinases

ReferenceB02196
Principal Investigator / Supervisor Professor Chris Abell
Co-Investigators /
Co-Supervisors
Institution University of Cambridge
DepartmentSchool of Clinical Medicine
Funding typeResearch
Value (£) 155,884
StatusCompleted
TypeResearch Grant
Start date 01/05/1995
End date 31/10/1998
Duration42 months

Abstract

i) to determine the mechanism of the type II dehydroquinases on the shikimate and quinate pathways. ii) to use 13C NMR spectroscopy to characterise enzyme bound intermediates on type I and type II dehydroquinases. iii) to probe the reactions of irreversible inhibitors of type I dehydroquinase.

Summary

unavailable
Committee Closed Committee - Biomolecular Sciences (BMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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