Award details

Acquisition of microbial genomics: Streptomyces coelicolor A3(2) sequencing project (Phase 1)

Reference	AMG09479
Principal Investigator / Supervisor	Dr Bart Barrell
Co-Investigators / Co-Supervisors
Institution	Wellcome Trust Sanger Institute
Department	Wellcome Trust Sanger Institute Department
Funding type	Research
Value (£)	60,000
Status	Completed
Type	Research Grant
Start date	01/08/1997
End date	01/02/1998
Duration	6 months

Abstract

This is a pilot study to sequence 10 cosmids from the cosmid library of the Streptomyces coelicolor A3(2) chromosome which will provide detailed costings for subsequent sequencing projects and highlight any potential problem areas. Particular issues to be addressed are: i) whether the high G:C composition of the genome (greater than 70 percent) will cause any particular problems that necessitate the use of a particular sequencing strategy; ii) whether information derived from the physical map about overlaps proves accurate at the sequencing level; iii) whether the size of the cloning vector (Supercos-1) affects the efficiency of sequencing; and iv) to determine a feasible timescale for completion of the whole sequencing project.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Acquisition of Microbial Genomics (AMG) [1996-1997]
Funding Scheme	X – not Funded via a specific Funding Scheme

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