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Microelectrochemical resonant mass sensors for generic specific binding analysis
Reference
ABY15453
Principal Investigator / Supervisor
Professor Calum McNeil
Co-Investigators /
Co-Supervisors
Professor J Burdess
,
Dr Alun Harris
,
Dr Jeanette Pritchard
Institution
Newcastle University
Department
Institute of Nanoscale Science and Techn
Funding type
Research
Value (£)
239,632
Status
Completed
Type
Research Grant
Start date
01/04/2002
End date
31/03/2004
Duration
24 months
Abstract
We propose to design, microfabricate and test a new concept for generic microelectromechanical systems (MEMS) resonant mass sensors based upon cyclically symmetric structures. We will use the frequency split of the degenerate modes of resonance for analysis of specific biological binding events. The generic applicability of sensors will be tested by application to two areas where a real clinical need exists: quantitative measurement of thyroglobulin mRNA (cDNA) for thyroid cancer management and monitoring and direct label-free immunodiagnostic assay of S-100 protein as a marker of brain damage following head injury.
Summary
unavailable
Committee
Closed Committee - Engineering & Biological Systems (EBS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
LINK: Analytical Biotechnology (ABY) [1995-2000]
Funding Scheme
X – not Funded via a specific Funding Scheme
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