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Immunosensors based on impedance measurement: rapid diagnosis of acute myocardial infarction using a new early biochemical marker
Reference
ABY10912
Principal Investigator / Supervisor
Professor Calum McNeil
Co-Investigators /
Co-Supervisors
Institution
Newcastle University
Department
Institute of Nanoscale Science and Techn
Funding type
Research
Value (£)
90,833
Status
Completed
Type
Research Grant
Start date
01/03/1999
End date
01/06/2001
Duration
27 months
Abstract
We propose to develop generic immunosensor devices, based on impedance measurement of enzyme-catalysed polymer degradation, and to test these devices thoroughly as a prelude to possible commercial exploitation. We will demonstrate the technology by application in an area which addresses a real and urgent clinical need: the rapid, early diagnosis of Acute Myocardial Infection. This will provide the fastest route to proving the sensitivity of the methodology. The expertise and interaction of this highly appropriate academic, clinical and industrial partnership has already proven highly effective in EC-funded clinical studies which evaluated Fatty Acid Binding Protein as an early marker for the diagnosis of AMI. We intend to carry out point-of-care FABP measurements and to assess the effect on patient management of the immediate availability of FABP values.
Summary
unavailable
Committee
Closed Committee - Engineering & Biological Systems (EBS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
LINK: Analytical Biotechnology (ABY) [1995-2000]
Funding Scheme
X – not Funded via a specific Funding Scheme
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