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Identification of genes required for late blight resistance in plants using novel virus-based gene silencing technology

Reference9810762
Principal Investigator / Supervisor Professor Sir David Baulcombe
Co-Investigators /
Co-Supervisors
Institution University of East Anglia
DepartmentSainsbury Laboratory
Funding typeResearch
Value (£) 131,354
StatusCompleted
TypeResearch Grant
Start date 01/11/1998
End date 01/11/2000
Duration24 months

Abstract

Virus-induced gene silencing will be exploited to clone genes in Nicotiana benthamiana that confer resistance against late blight. Plants will be infected with a library of PVX constructs carrying inserts of N. benthamiana mRNAs. Failure of these plants to recognise the protein of P. infestans that elicits the resistance reaction will indicate that there has been suppression of genes required for late blight resistance. To clone these genes the inserts will be recovered from the infecting virus used as probes in N. benthamiana genomic libraries. The isolated genes will be used to transfer late blight resistance into potato and tomato.

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative ROPA 1998 (ROPA1998) [1998]
Funding SchemeX – not Funded via a specific Funding Scheme
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