Award details

Application of a novel gene mapping tool (amplified fragment length polymorphism) to identify a clock gene in mammals

Reference9810688
Principal Investigator / Supervisor Professor Andrew Loudon
Co-Investigators /
Co-Supervisors
Institution The University of Manchester
DepartmentLife Sciences
Funding typeResearch
Value (£) 110,640
StatusCompleted
TypeResearch Grant
Start date 01/01/1999
End date 01/01/2001
Duration24 months

Abstract

The project aims to develop amplified fragment length polymorphism (AFLP) as a way of identifying markers linked to a circadian clock gene (tau) in an unexplored genome (hamster). Use of the AFLP method will permit linkage determination of the tau gene, identification of appropriate genomic fragments and should ultimately lead to the cloning of this important gene. This application of the AFLP method is novel (currently used only in plants) and permits the production of a dense population of markers for mapping purposes in a vertebrate.

Summary

unavailable
Committee Closed Committee - Genes & Developmental Biology (GDB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative ROPA 1998 (ROPA1998) [1998]
Funding SchemeX – not Funded via a specific Funding Scheme
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