BBSRC Portfolio Analyser
Award details
Micro stopped-flow and flash kinetic infrared spectroscopy of reacting systems
Reference
9708975
Principal Investigator / Supervisor
Professor C Wharton
Co-Investigators /
Co-Supervisors
Institution
University of Birmingham
Department
Sch of Geography, Earth & Env Sciences
Funding type
Research
Value (£)
119,176
Status
Completed
Type
Research Grant
Start date
01/04/1998
End date
01/01/2001
Duration
33 months
Abstract
This proposal aims to address the widely appreciated need for more structural information concerning the behaviour of dynamic biological systems. To this end it is proposed to construct a dispersive fast kinetic IR spectrometer interfaced with a micro stopped-flow system. The sample volume per shot will be ca. 5-10 microlitres l compared with the 50 microlitres l currently required in the stopped-flow FTIR system we have recently developed and the deadtime will be ca. 1 ms. The spectrometer will be used to provide structural information concerning enzyme reaction and protein folding intermediates in reactive conditions.
Summary
unavailable
Committee
Closed Committee - Biomolecular Sciences (BMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
ROPA 1997 (ROPA1997) [1997]
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search