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A functional screen for novel genes involved in haematopoiesis
Reference
9708828
Principal Investigator / Supervisor
Professor Lesley Forrester
Co-Investigators /
Co-Supervisors
Institution
University of Edinburgh
Department
Dept of Clinical Oncology
Funding type
Research
Value (£)
79,446
Status
Completed
Type
Research Grant
Start date
01/01/1998
End date
01/05/2000
Duration
28 months
Abstract
We propose to develop a functional screen to test novel cDNA sequences for effect on haematopoietic commitment and differentiation of embryonic stem cells. We have access to a rich source of novel cDNA sequences that are likely to be expressed and functional in haematopoietic lineages. Stable expression of those cDNAs in ES cells will be achieved using a new episomal vector system. It should be possible to assay for molecules that have either a positive or negative effect haematopoietic development.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
ROPA 1997 (ROPA1997) [1997]
Funding Scheme
X – not Funded via a specific Funding Scheme
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