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Analysis of cell-specific gene expression and sub-cellular protein localisation in Streptomyces coelicolor
Reference
9708822
Principal Investigator / Supervisor
Professor Sir David Hopwood
Co-Investigators /
Co-Supervisors
Institution
John Innes Centre
Department
John Innes Centre Department
Funding type
Research
Value (£)
40,880
Status
Completed
Type
Research Grant
Start date
11/05/1998
End date
11/05/1999
Duration
12 months
Abstract
The aim of this work is to develop the green fluorescent protein (GFP) from the jellyfish Aequorea victoria as a reporter for Streptomyces, in order to localise by confocal microscopy the expression of individual genes within whole, living colonies during development (transcriptional fusions), particularly those involved in differentiation and antibiotic production, and to define the subcellular location of individual proteins (translational fusions), particularly those involved in cell division and chromosome segregation.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
ROPA 1997 (ROPA1997) [1997]
Funding Scheme
X – not Funded via a specific Funding Scheme
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