BBSRC Portfolio Analyser
Award details
Gold/SAM nanostructures: a potential delivery system for photodynamic agents
Reference
0014808
Principal Investigator / Supervisor
Professor David Russell
Co-Investigators /
Co-Supervisors
Institution
University of East Anglia
Department
Chemistry
Funding type
Research
Value (£)
74,468
Status
Completed
Type
Research Grant
Start date
08/01/2001
End date
08/07/2002
Duration
18 months
Abstract
The proposed research will develop methods for the formation and characterisation of gold colloidal nanoparticles coated with a photosensitizer self-assembled monolayer (SAM). The proposed methods will enable the synthesis of SAM coated particles in the 1-10 nm size regime. Generation of the cytotoxic species, singlet oxygen, from the surface of the photosensitizer coated nanoparticles will be achieved using laser excitation at 690 nm to elicit a photodynamic response. Assessment will be made as to whether such gold/SAM nanostructures could be a useful vehicle for the delivery of macromolecular photodynamic drugs.
Summary
unavailable
Committee
Closed Committee - Engineering & Biological Systems (EBS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
ROPA 2000 (ROPA2000) [2000]
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search